Panama City Vacations from $650

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Your Panama City Vacation

The tropical climate, cosmopolitan vibe and rich history are three of the many reasons why people love this coastal city. Discover this incredible destination as you please with a Panama City vacation package. Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama are just a few of the sights worth exploring during your trip to Panama City. A few quick clicks is all it takes to put together your dream Panama City vacation on Expedia.

The Latest Panama City vacation packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,372, price is now $650 per person
$650
per person
Jan 9 - Jan 16
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
20/10 Exceptional! (1 review)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,541, price is now $1,290 per person
$1,290
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
18/10 Exceptional! (1,002 reviews)
Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city.

Reviewed on Nov 16, 2025

Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
Price was $1,747, price is now $1,102 per person
$1,102
per person
Feb 1 - Feb 7
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
17.6/10 Exceptional! (149 reviews)
Loved this property, and will definitely return!

Reviewed on Aug 14, 2025

Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Save 100% on your flight
Price was $1,180, price is now $765 per person
$765
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
18.8/10 Exceptional! (124 reviews)
The room was wonderful, the food fantastic, And the staff was warm and friendly. We can't wait to go back.

Reviewed on Nov 12, 2025

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,339, price is now $870 per person
$870
per person
Feb 4 - Feb 10
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
17.6/10 Exceptional! (3 reviews)
Reseña sugerida: La propiedad está muy bonita y completamente remodelada, lo cual se agradece mucho. Sin embargo, hubo varios detalles que no permitieron que mi estadía fuera 100% cómoda. • En los baños salía un olor desagradable de las cañerías, lo que impregnaba el ambiente. • Las baterías del control de aire acondicionado de un cuarto estaban agotadas y tuve que usar el control de otro. • La pared de piedra junto a la cama desprende un polvo fino que cae sobre la cama. • Para una estadía de 9 días, la cantidad de toallas (2), papel higiénico y bolsas de basura proporcionadas fue muy limitada. • La secadora no funcionaba, por lo que tuve que secar la ropa en otra parte de la casa. • Debido a la ubicación, se escucha bastante ruido en el apartamento. En general, la propiedad tiene mucho potencial y está bien ubicada, pero considero importante que se atiendan estos detalles para que la experiencia sea más placentera.

Reviewed on Sep 8, 2025

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
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Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Find hotels in Casco Viejo

Discover the most popular places to visit in Panama City

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4.5/5(456 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa

What to do in Panama City

Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

$155
per adult
90% of travellers recommend
Panama City: Poin Full Package Experience
Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

$74
per adult
90% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
Monkey and Sloth Jungle Habitat Panama Tour

Monkey and Sloth Jungle Habitat Panama Tour

$60
per adult
100% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
See all activities in Panama City

Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from Nov 23 to Nov 24
$131 total
Nov 23 - Nov 24
Total with taxes and fees
9/10 Wonderful! (4,500 reviews)
Great breakfast, big rooms and view from them

Reviewed on Nov 13, 2025

Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $189 total per night from Dec 1 to Dec 2
$189 total
Dec 1 - Dec 2
Total with taxes and fees
8.8/10 Excellent! (1,003 reviews)
Great service and attention

Reviewed on Nov 17, 2025

Waldorf Astoria Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $125 total per night from Dec 12 to Dec 13
$125 total
Dec 12 - Dec 13
Total with taxes and fees
8.4/10 Very Good! (1,200 reviews)
The room was spotless and the staff was courteous

Reviewed on Nov 14, 2025

Megapolis Hotel Panamá
See all 1,517 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Panama City Vacation Packages

Panama City Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Veracruz Beach, Metropolitan Cathedral of Panama and Soberania National Park

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Frequently asked questions

How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination from $650 on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
January, July and December are great times to look for cheap Panama City vacation packages. Traveling in less busy periods means you can typically find lower prices on hotels and flights.
How many days is enough for Panama City?
Panama City vacations can be as short or long as you like, but to get a real feel for this destination, we reckon 3 days is about right. In this timeframe, you can visit headline attractions like Frank Gehry Biodiversity Museum and Museum of History Panama as well as underrated gems. Don't skip neighborhoods such as Campo Alegre and El Cangrejo either. If you're clever with your time, you can even take a day trip from Panama City too.
Is it worth booking a vacation package to Panama City?
Panama City has everything you need for an amazing break — culture, nature and nightlife are just the start. Whether you want to visit attractions like Metropolitan Cathedral of Panama and Albrook Shopping Mall, or venture off the beaten track, you'll have plenty to experience on your Panama City vacation.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?

  1. Pick your travel dates: What you want to do in Panama City and your favorite season can help you decide when to get away.
  2. Figure out your budget: Ensure you have enough money to cover everything from meals and transportation to activities and flights. Your accommodations will probably be the biggest expense during your trip to Panama City.
  3. Organize your Panama City getaway with Expedia's trip planning tool: Search for and book hotels and experiences all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Panama City together.
  4. Decide how long to go away for: Now that you're more familiar with Panama City, you can figure out the perfect length of your break. Put together a draft plan and allocate enough time to cover everything you want to see.
  5. Bundle your hotel and flights: Awesome destination, check. Length of stay, check. All that's left is to pick a Panama City vacation package that brings all your bookings together.
  6. Book any activities or day trips: Here's the fun part — organizing everything you want to do and see. Check out some of the incredible things to do in Panama City and reserve your tickets in advance to save time (and maybe some spending money too!).

Does Expedia offer Book Now, Pay Later Panama City vacation packages?
Set off on your dream trip to Panama City with Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or hold off until the next payday — we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily budget for your trip and snap up travel deals before they sell out.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.